. Author manuscript; available in PMC: 2021 Apr 1.

Published in final edited form as: Lifetime Data Anal. 2019 Apr 12;26(2):266–291. doi: 10.1007/s10985-019-09470-4

Table B.4.

Variance, calendar time and information fraction corresponding to the other endpoint’s information fraction

Endpoint	Variance, corresponding calendar time and information fraction		1st analysis	Final analysis
Virologic failure (OC1)	information fraction		0.5	1.0
	Corresponding Calendar time (week)		45.5	96.0
	OC1	$V_{11}^{0 (ℓ)} (τ_{ℓ})$	0.0252	0.0499
	OC2 (Regimen failure)	$V_{22}^{0 (ℓ)} (τ_{ℓ})$	0.0539	0.0998
	OC2 (Regimen failure)	Corresponding information fraction	0.5400	1.0
Regimen failure (OC2)	information fraction		0.5	1.0
	Corresponding Calendar time (week)		42.0	96.0
	OC1 (Virologic failure)	$V_{11}^{0 (ℓ)} (τ_{ℓ})$	0.0233	0.0499
	OC1 (Virologic failure)	Corresponding information fraction	0.4675	1.0
	OC2	$V_{22}^{0 (ℓ)} (τ_{ℓ})$	0.0502	0.0998