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. 2020 Sep 11;11:557312. doi: 10.3389/fphar.2020.557312

Figure 4.

Figure 4

M10 down-regulated the IL-6 and NF-κB signaling pathways in the inflamed colonic epithelium. (A) M10 with 25, 50, and 100 mg/kg suppressed the IL-6 signaling pathway in colonic mucosal cells. (B) M10 down-regulated NF-κB signaling pathway. N = 6. *p < 0.05, **p < 0.01 vs. model mice as well as Myricetin- and Mesalazine-treated mice.