Table 1. Cytotoxic activity of EGFR-specific recombinant antibody-drug conjugates.

EGFR-specific immunotherapy	Construct name	Disease model	IC50value	References
Recombinant Antibody-Drug Conjugates
	425(scFv)-SNAP-AURIF	Epidermoid carcinoma	8 nM	[107, 149]
		Triple-negative breast cancer	2.6 nM–4 nM
		Rhabdomyosarcoma	8 nM
	1711(scFv)-SNAP-AURIF	Epidermoid carcinoma	12 nM	[107]
		Triple-negative breast cancer	4 nM
		Rhabdomyosarcoma	4 nM
	αHER2(scFv)-SNAP-AURIF	Breast cancer	0.6 nM	[149]