Table 3. Mitochondrial function.
| CON-SALINE | CON-SS-31 | TB-SALINE | TB-SS-31 | |
|---|---|---|---|---|
| Heart | ||||
| State 3 (nmoles O2/mg/min) | 17.50 ± 1.12 | 16.76 ± 0.04 | 10.09 ± 0.54* | 15.57 ± 0.85 |
| State 4 (nmoles O2/mg/min) | 2.52 ± 0.19 | 2.31 ± 0.13 | 3.45 ± 0.34§ | 2.78 ± 0.33 |
| RCR (State 3/State 4) | 7.09 ± 0.40 | 7.27 ± 0.36 | 3.09 ± 0.28* | 5.87 ± 0.60 |
| Diaphragm | ||||
| State 3 (nmoles O2/mg/min) | 17.89 ± 1.02 | 17.21 ± 1.29 | 11.65 ± 0.95# | 15.19 ± 2.05 |
| State 4 (nmoles O2/mg/min) | 2.46 ± 0.24 | 2.48 ± 0.16 | 3.75 ± 0.36# | 2.79 ± 0.42 |
| RCR (State 3/State 4) | 7.58 ± 0.46 | 6.93 ± 0.21 | 3.17 ± 0.20* | 5.82 ± 0.70 |
Cardiac and diaphragm muscle mitochondria state 3 respiration, state 4 respiration and respiratory control ratio (RCR). Values are presented as means ± SEM. *significantly different versus all groups (p < 0.05); #significantly different versus CON-SALINE and CON-SS-31 (p < 0.05). §significantly different versus CON-SS-31 (p < 0.05).