Table 3.
Pathology Results of Patients With SMTC.
| Factors | Total (n = 125) | Lateral lymph node metastases | p | |
|---|---|---|---|---|
| (+) (n = 49) | (−) (n = 76) | |||
| Left/right lobe (n) | 65/60 | 25/24 | 40/36 | 0.860 |
| Multifocality n(%) | 20 (16.0%) | 9 (18.4%) | 11 (14.5%) | 0.562 |
| Bilaterality n(%) | 17 (13.6%) | 7 (14.3%) | 10 (13.2%) | 0.857 |
| Major tumor size (cm) | 2.0 ± 1.3 | 2.2 ± 1.6 | 1.8 ± 1.1 | 0.065 |
| Total tumor size (cm) | 2.2 ± 1.8 | 2.5 ± 2.3 | 1.9 ± 1.3 | 0.087 |
| Capsular invasion n(%) | 34 (27.2%) | 22 (44.9%) | 12 (15.8%) | <0.001 |
| Extrathyroidal invasion n(%) | 11 (8.8%) | 8 (16.3%) | 3 (3.9%) | 0.039 |
| Ki67 ≥5% n(%) | 20 (16.0%) | 9 (18.4%) | 11 (14.5%) | 0.562 |
| Positive central LNM n(%) | 59 (47.2%) | 39 (79.6%) | 20 (26.3%) | <0.001 |
SMTC: sporadic medullary thyroid carcinoma; LNM: lymph node metastases.
The continuous variables are presented as the means ± standard deviations.