FIGURE 5.
ASPS-1 cells express markers involved in angiogenesis, metastasis, cell proliferation, and skeletal muscle. Cells were grown in coverglass chambers processed as described in Materials and Methods. Illustrated ASPS-1 proteins are ASPL-TFE3 type 1 fusion protein; ADAM9 (metastasis); PRL and PCSK1 (cell proliferation); ITGB1BP3 and TRIM63 (tissue restricted); and HIF-1-α, MDK, c-MET and VEGF (angiogenesis). ASPS indicates alveolar soft part sarcoma; ASPL-TFE3, alveolar soft part locus-transcription factor E3.