Skip to main content
. Author manuscript; available in PMC: 2020 Sep 25.
Published in final edited form as: J Pediatr Hematol Oncol. 2011 Jul;33(5):360–368. doi: 10.1097/MPH.0b013e3182002f9f

FIGURE 6.

FIGURE 6.

In vivo tumorigenicity and immunohistochemistry of selected markers in ASPS tumors produced by ASPS-1. ASPS-1 cells were injected subcutaneously into female NOD.SCID mice and tumors harvested 3 months later. Tumors were fixed in 10% neutral-buffered formalin and examined for both diagnostic (periodic acid-Schiff/Diastase, nuclear reactivity to ASPL-TFE3 type 1, and ASPL-TFE3 type 2 antibodies) and immunohistochemical markers (PRL, ITGB1BP3, TRIM63, HIF-1-α, MDK, c-MET, and VEGF) as described previously.6,8,12 ASPS indicates alveolar soft part sarcoma; ASPL-TFE3, alveolar soft part locus-transcription factor E3.