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. 2021 Mar 4;57(3):2002226. doi: 10.1183/13993003.02226-2020

TABLE 5.

Significant factors affecting the admission duration (days)

Univariate Multivariate VIF
β coefficient (95% CI) p-value β coefficient (95% CI) p-value
Among all COVID-19 patients#
 Asthma 0.947 (−0.693–2.587) 0.258 −0.342 (−1.993–1.309) 0.685
Among asthma patients
 ICS alone
  Past year −1.385 (−5.306–2.537) 0.487 −1.083 (−6.096–3.929) 0.670 1.630
  Past 2 months −2.805 (−6.869–1.260) 0.175 −3.579 (−9.083–1.925) 0.201 1.822
 ICS–LABA
  Past year 0.611 (−3.094–4.316) 0.746 −0.794 (−5.220–3.631) 0.724 1.425
  Past 2 months 0.055 (−3.707–3.818) 0.977 −1.994 (−6.675–2.688) 0.402 1.551
 Oral LABA
  Past year −3.899 (−7.636–−0.162) 0.041* −3.503 (−7.703–0.696) 0.102 1.238
  Past 2 months −4.248 (−8.070–−0.428) 0.030* −3.744 (−8.214–0.726) 0.100 1.341
 Patch LABA
  Past year 0.520 (−4.095–5.135) 0.825 4.516 (−1.292–10.324) 0.127 1.583
  Past 2 months −0.948 (−5.804–3.908) 0.701 3.302 (−3.208–9.811) 0.318 1.799
 LTRA
  Past year −0.273 (−4.354–3.809) 0.895 0.662 (−3.952–5.277) 0.777 1.278
  Past 2 months −1.812 (−5.626–2.002) 0.350 −0.620 (−5.184–3.944) 0.789 1.428
 Inhaled SABA
  Past year −0.573 (−4.286–3.141) 0.762 1.076 (−3.748–5.900) 0.661 1.686
  Past 2 months 0.100 (−3.697–3.896) 0.959 3.915 (−1.347–9.177) 0.144 1.924
 Oral SABA
  Past year 4.088 (−1.119–9.295) 0.123 5.734 (0.014–11.453) 0.049* 1.193
  Past 2 months 3.149 (−2.225–8.523) 0.249 4.893 (−1.210–10.997) 0.115 1.284
 Xanthine
  Past year 1.036 (−2.569–4.641) 0.572 −0.129 (−4.095–3.836) 0.949 1.208
  Past 2 months 0.682 (−2.937–4.300) 0.711 −0.225 (−4.327–3.878) 0.914 1.287
 Inhaled LAMA
  Past year 0.450 (−5.210–6.111) 0.876 −3.046 (−10.192–4.099) 0.402 1.593
  Past 2 months 0.450 (−5.210–6.111) 0.876 −2.431 (−9.623–4.760) 0.506 1.617
 Severity of asthma (reference step 1)
  Step 2 5.044 (−0.301–10.390) 0.064 4.565 (−1.127–10.258) 0.115 1.668
  Step 3 4.000 (−2.470–10.470) 0.224 2.739 (−3.998–9.475) 0.424 1.397
  Step 4 1.238 (−3.308–5.783) 0.592 0.976 (−3.802–5.753) 0.688 1.759
  Step 5 19.583 (6.011–33.155) 0.005* 18.414 (4.031–32.796) 0.012* 1.171

VIF: variance inflation factor; COVID-19: coronavirus disease 2019; ICS: inhaled corticosteroid; LABA: long-acting β2-agonist; LTRA: leukotriene receptor antagonist; SABA: short-acting β2-agonist; LAMA: long-acting muscarinic antagonist. #: adjusted for age, sex and underlying disease; : adjusted for age, sex, underlying disease and asthma medications/severity. *: p<0.05.