FIGURE 6.

Maternal diet‐induced obesity reduced basal nitric oxide production in thoracic aorta from adult male offspring fed the western diet. Phenylephrine (PE)‐induced contraction in aortic rings, with or without the nitric oxide synthase inhibitor NG‐nitro‐Larginine methyl ester (L‐NAME), from (a,b) offspring fed the western diet or (d,e) control diet. Difference in the area under the curve (AUC) between contraction curves with and without L‐NAME in offspring fed the (c) western diet or (f) control diet. For contraction curves, symbols represent mean ± SD for each group at each PE concentration. For bar graphs, values for each mouse presented; bar graphs represent mean ± SD (n = 5–6/group)