FIGURE 2.

Key components of the microglial sensome associated with SCZ. The microglial sensome is a group of receptors and proteins that allow microglia to sense and respond to their changing environment, facilitating the diverse roles of microglial as well as their complex interactions with multiple cell-types in the brain. Components of the microglia sensome can be categorized to include purinergic, cytokine, Fc, pattern recognition, extracellular matrix, and cell-cell interaction receptors and ligands, among others not listed here. Future work could aim at targeting the microglial sensome to normalize microglial function in SCZ.