Table 2.
Baseline echocardiographic parameters of STICH Trial Hypothesis 2 patients by mitral regurgitation severity.
| Characteristics | Baseline MR Severity | p-value | ||
|---|---|---|---|---|
| Grade 0 (N=221) | Grade 1 (N=435) | Grade 2–4 (N=211) | ||
| LVEF (%) (n=671) | 32.4±8.5 | 29.5±7.8 | 26.9±7.7 | <0.001 |
| LVEDV index (mL/m2) (n=671) | 106.3±32.5 | 114.8±33.2 | 130.1±40.6 | <0.001 |
| LVESV index (mL/m2) (n=671) | 73.1±27.9 | 82.0±29.0 | 96.3±35.7 | <0.001 |
| LA volume index (mL/m2) (n=546) | 34.0±9.9 | 41.5±13.0 | 50.9±19.6 | <0.001 |
| E/A ratio (n=689) | 0.9±0.6 | 1.3±0.9 | 1.8±1.0 | <0.001 |
| E/e' septal (n=396) | 12.7±4.9 | 16.7±8.7 | 22.2±12.0 | <0.001 |
| Estimated PA systolic pressure (mmHg) (n=197) | 33.0±9.0 | 41.4±14.9 | 46.2±15.1 | <0.001 |
Values in table are mean ± standard deviation (SD).
LA, left atrial; LVEDV, left ventricular end-diastolic volume; LVEF, left ventricular ejection fraction; LVESV, left ventricular end-systolic volume; MR, mitral regurgitation; PA; pulmonary artery.