Table 1.
Baseline Characteristics of the Participants Per Cohort
| LASA (N = 1,736) | InCHIANTI (N = 843) | Rotterdam Study (N = 4,597) | |
|---|---|---|---|
| Age at baseline (years), Mean (SD) | 69.8 (8.1) | 72.4 (7.2) | 67.8 (7.4) |
| Female, N (%) | 896 (51.6%) | 470 (55.7%) | 2,617 (56.9%) |
| APOE ɛ 4 carriers, N (%) | 467 (26.9%) | 128 (15.2%) | 1,268 (27.6%) |
| Physical activity | Range (MET h/wk) | N (%) | Range (MET h/wk) |
| Low | 0.2–41.4 | 122 (14.5%) | 2.8–63.4 |
| Moderate | 41.5–74.8 | 383 (45.4%) | 63.5–99.3 |
| High | 74.9–325.5 | 338 (40.1%) | 99.4–296.3 |
| MMSE at baseline, Mean (SD) | 27.5 (2.1) | 25.9 (2.7) | 27.9 (1.7) |
| Education, N (%) | |||
| Low (<9 y) | 685 (39.5%) | 742 (88.0%) | 505 (11.1%) |
| Intermediate (9–12 y) | 835 (48.2%) | 43 (5.1%) | 2,025 (44.4%) |
| High (>12 y) | 214 (12.3%) | 58 (6.9%) | 2,030 (44.5%) |
| Depression, N (%) | 213 (12.3%) | 245 (29.1%) | 428 (9.4%) |
| Number of chronic disease, N (%) | |||
| 0–1 | 1,343 (77.4%) | 545 (69.3%) | 4,080 (88.8%) |
| 2 | 279 (16.1%) | 147 (18.7%) | 428 (9.3%) |
| >2 | 113 (6.5%) | 95 (12.0%) | 89 (1.9%) |
Note: Low physical activity(PA) corresponds to the inactive category for InCHIANTI and first tertile for LASA and RS; Moderate PA corresponds to the light PA category for InCHIANTI and to the second tertile for LASA and RS; High PA corresponds to the moderate–high category for InCHIANTI and the highest tertile in LASA and RS.