Table 4. Non-inferiority concordance study for clinical validity for the detection of EGFR exon 19 deletions and L858R substitutions in NSCLC (n = 177).
Comparison | PPA | NPA |
---|---|---|
Ref2|Ref1 | 95.3% | 98.9% |
Ref1|Ref2 | 96.1% | 98.7% |
CGP|Ref1 | 97.7% | 95.6% |
CGP|Ref2 | 97.7% | 95.4% |
CGP = FoundationOne Liquid CDx; NPA = negative percent agreement; PPA = positive percent agreement; Ref1 = reference assay replicate 1; Ref2 = reference assay replicate 2.