Fig 4.

[A] Representative agarose gel electrophoresis photograph showing the PCR amplification of exon 4,5,6,7,8 and 9 of p53 gene for mutation analysis in cervical cancer cases. [B] Representative electrophoregrams showing the presence of Arg/Arg, Arg/Pro heterozygous and Pro/Pro genotype based on p53 exon 4 sequencing analysis in the studied Cervical cancer patient population cohort, [C] Box-plot analysis showing the difference in pattern of p53 mRNA expression fold change profile in Arg/Pro heterozygous or Arg/Arg homozygous genotype compared to the Pro/Pro genotype in HPV+ve and HPV-ve cases, thereby signifying the importance of rs1042522 polymorphism in the northeast Indian population.