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. 2020 Sep 25;15(9):e0238500. doi: 10.1371/journal.pone.0238500

Table 3. Methylation status in affected area compared to non-neoplastic control area in HPV positive cases.

Staging of Cervical Cancer cases N Hyper-methylation Hypo-methylation No change
Grade II 31 12[38.7] 5 [16.1] 14[45.1]
Grade III 27 7[25.92] 9[33.33] 11[40.74]
Grade IV 14 1[7.14] 5[35.71] 8[57.14]