Table 4. Characteristics of the patients (n = 150) with OTSCC treated in curative intent, including number of cases, percent of patients with disease-specific survival (DSS) with p-value (p), 95% confidence interval (CI), and hazard ratio (HR).
| Characteristic | No. of cases (%) | 5-year DSS % | HR (CI) p | |
|---|---|---|---|---|
| Gender | Male | 92 (61.3) | 70.7 | 1.130 (0.622–2.051), p = 0.702 |
| Female | 58 (38.7) | 69.0 | ||
| Age (year) group | ≤ 50 | 29 (19.3) | 79.3 | 1.382 (1.072–1.782) p = 0.015 |
| 51–60 | 29 (19.3) | 65.5 | ||
| 61–70 | 44 (29.3) | 70.5 | ||
| 71–80 | 31 (20.7) | 67.7 | ||
| ≥81 | 17 (11.3) | 64.7 | ||
| T old classification | T1 | 91 (60.7) | 70.3 | 1.063 (0.666–1.696) p = 0.806 |
| T2 | 28 (18.7) | 75.0 | ||
| T3 | 8 (5.3) | 75.0. | ||
| T4 | 2 (1.3) | 50.0 | ||
| T unknown | 21 (14.0) | |||
| T 8 ed classification | pT1 | 48 (32.0) | 87.5 | 1.734 (1.132–2.657) p = 0.006 |
| pT2 | 53 (35.3) | 64.2 | ||
| pT3 | 34 (22.7) | 64.7 | ||
| pT unknown | 15 (10.0) | |||
| N | N0 | 108 (72.0) | 82.4 | 4.639 (2.541–8.471) p = 0.001 |
| N+ | 40 (26.7) | 37.5 | ||
| Unknown | 2 (1.3) | |||
| TB 2-tier | Low (Bd1) | 112 (74.7) | 76.8 | 2.269 (1.182–4.356) p = 0.016 |
| High (Bd2+Bd3) | 29 (19.3) | 51.7 | ||
| Unknown | 9 (6.0) | |||
| TB 3-tier | Bd1 <5 | 112 (74.7) | 76.8 | 1.847 (1.242–2.748) p = 0.002 |
| Bd2 ≥5 and<10 | 18 (12.0) | 66.7 | ||
| Bd3 ≥ 10 | 11 (7.3) | 27.3 | ||
| Unknown | 9 (6.0) | |||
| DOI 2-tier | < 4 mm | 29 (19.3) | 86.2 | 2.172 (0.769–6.133) p = 0.090 |
| ≥4 mm | 103 (68.7) | 68.0 | ||
| Unknown | 18 (12.0) | |||
| DOI 3-tier | < 5 mm | 47 (31.3) | 87.2 | 1.634 (1.072–2.491) p = 0.015 |
| ≥5 mm and<10 mm | 52 (34.7) | 61.5 | ||
| ≥10 mm | 33 (22.0) | 66.7 | ||
| Unknown | 18 (12.0) | |||
| Combined TB/DOI*-score | TB/DOI-0 | 24 (16.0) | 91.7 | 1.673 (0.969–2.891) p = 0.013 |
| TB/DOI-1 | 91 (60.7) | 67.0 | ||
| TB/DOI-2 | 20 (13.3) | 60.0 | ||
| Unknown | 15 (10.0) |
* Almangush et al 2014.