Table 2.
Change in clinical parameters after parathyroidectomy.
| Variables | Asymptomatic PHPT, n = 63 | Symptomatic PHPT, n = 28 | P |
|---|---|---|---|
| ∆ BMI (kg/m2) | 0.48 ± 1.31 | 0.19 ± 0.85 | 0.282 |
| ∆ Calcium (mg/dL) | –1.43 ± 0.68 | -3.32 ± 5.82 | 0.012 |
| ∆ Phosphorus (mg/dL) | 0.73 ± 0.49 | -0.89 ± 0.52 | 0.168 |
| ∆ iPTH (pg/dL) | –128.71 ± 122.86 | -297.51 ± 310.81 | <0.001 |
| ∆ ALP (mg/dL) | –22.82 ± 27.06 | -78.25 ± 66.08 | <0.001 |
| ∆ Magnesium (mg/dL) | –0.13 ± 0.27 | 0.03 ± 0.24 | 0.486 |
| ∆ 25(OH)D | 14.84 ± 24.12 | 19.01 ± 9.17 | 0.379 |
| ∆ Lumbar spine BMD (g/cm3) % | 4.65 (–10.00 to 30.65) | 10.83 (-6.72 - 70.08) | 0.016 |
| ∆ Total hip BMD (g/cm3) % | 3.75 (–11.57 to 21.29) | 6.57 (-7.53 - 51.98) | 0.124 |
| ∆ Femoral neck BMD (g/cm3) % | 4.37 (–11.21 to 30.04) | 12.61 (-14.17 - 54.85) | 0.005 |
| ∆ Lumbar spine BMD T-score | 0.30 ± 0.77 | 0.65 ± 0.60 | 0.039 |
| ∆ Total hip BMD T-score | 0.26 ± 0.51 | 0.54 ± 0.55 | 0.021 |
| ∆ Femoral neck BMD T-score | 0.36 ± 0.67 | 0.98 ± 0.94 | 0.001 |
| ∆ Osteoporosis at lumbar spine (%) | 25.8 | 9.4 | 0.014 |
| ∆ Osteoporosis at total hip (%) | 22.4 | 5.3 | 0.007 |
| ∆ Osteoporosis at femoral neck (%) | 22.1 | 8.2 | 0.009 |
| ∆ Osteoporosis of at least one site (%) | 22.1 | 6.3 | 0.008 |
Continuous variables are presented as mean ± standard deviation (SD). Categorical variables are presented as percentage (%).
Difference (Δ) is shown as change in values before and after treatment (latter value minus former value).
BMI, Body mass index; ALP, alkaline phosphatase; iPTH, intact parathyroid hormone, BMD, bone mineral density; 25(OH)D, 25-hydroxy-vitamin D.