Table 4.
DMR results from Comb-p (regions with Model 1 adjusted p< 0.01 shown) for the baseline phylloquinone EWAS.
| Locus | # CpGs | Annotated gene | Adj. P-value (Model 1) | Adj. P-value (Model 2) |
|---|---|---|---|---|
| chr20:43936662-43938184 | 18 | MATN4; RBPJL | 5.81E-15 | 2.38E-09 |
| chr20:62366418-62368565 | 16 | ZGPAT | 7.89E-05 | No DMR* |
| chr11:7041079-7042021 | 20 | ZNF214; NLRP14 | 3.41E-04 | 3.47E-03 |
| chr12:131616936-131617481 | 5 | GPR133 | 5.44E-04 | 9.99E-01 |
| chr19:39465820-39467435 | 15 | FBXO17 | 6.08E-04 | 8.15E-01 |
| chr16:2907516-2908715 | 13 | PRSS22 | 9.36E-04 | 3.16E-02 |
| chr19:55280671-55281274 | 5 | KIR2DL1; KIR3DP1 | 1.03E-03 | 7.94E-04 |
| chr6:33871421-33872861 | 9 | 2.71E-03 | 1.4E-04 | |
| chr15:22833148-22833975 | 12 | TUBGCP5 | 2.93E-03 | 1.09E-01 |
| chr22:37770943-37772106 | 7 | ELFN2 | 3.33E-03 | 9E-01 |
| chr21:22369309-22370,864 | 11 | NCAM2 | 3.43E-03 | 1.8E-01 |
| chr14:97923970-97925676 | 11 | 3.49E-03 | 1.37E-04 | |
| chr12:113902261-113903973 | 11 | LHX5 | 4.47E-03 | No DMR* |
| chr16:14402938-14403425 | 8 | MIR365-1 | 4.89E-03 | 4.65E-02 |
| chr21:47294738-47295375 | 4 | PCBP3 | 5.76E-03 | 7.08E-01 |
| chr14:94404915-94406618 | 7 | ASB2 | 6.32E-03 | No DMR* |
| chr2:105852797-105854051 | 9 | 7.00E-03 | 2.32E-01 | |
| chr2:99388232-99388712 | 4 | LOC101927070 | 7.28E-03 | 3.02E-02 |
| chr17:79494,627-79496290 | 12 | FSCN2 | 8.34E-03 | 1E+00 |
| chr3:141086,819-141087363 | 6 | ZBTB38 | 9.16E-03 | 2.35E-02 |
| chr7:156794878-156796967 | 10 | 9.17E-03 | No DMR* | |
| chr20:57425514-57428473 | 66 | GNAS; GNASAS | 9.28E-03 | No DMR* |
| chr11:44327868-44328423 | 3 | ALX4 | 9.78E-03 | 7E-01 |
*No DMR signifies that a DMR was not identified using the p-values from Model 2.