Fig. 1.

The majority of P. falciparum genes are periodically transcribed. Four strains of P. falciparum were cultured in vitro and transcriptionally profiled using time-series RNA-seq. Periodic genes were identified in each strain by JTK_CYCLE, and strain-intrinsic period length is evident. Each vertical line represents a time point, and gene expression is displayed horizontally. Expression values are mean-normalized for each gene and depicted as a z-score of standard deviations from the mean. Genes are ordered per strain by peak expression time.