Table 1.
Comparisons of Baseline Characteristics According to the Presence or Absence of Depression After ICH
| Variables | Total (n=372) | Depression After ICH | P value | |
|---|---|---|---|---|
| Depression | Non-Depression | |||
| Demographics | ||||
| Age, years, median (IQR) | 66 (56, 75) | 70 (57, 76) | 65 (56, 74) | 0.100 |
| Gender, Male, n (%) | 232 (62.4) | 63 (58.9) | 169 (63.8) | 0.378 |
| Education years, median (IQR) | 5 (4, 9) | 5 (4, 9) | 6 (4, 10) | 0.117 |
| Married, n (%) | 322 (86.6) | 92 (86.0) | 230 (86.8) | 0.347 |
| Medical history, n (%) | ||||
| Hypertension | 255 (68.5) | 74 (69.2) | 181 (68.3) | 0.872 |
| Diabetes | 50 (13.4) | 16 (15.0) | 34 (12.8) | 0.587 |
| Hyperlipidemia | 138 (37.1) | 44 (41.1) | 94 (35.5) | 0.307 |
| Coronary heart disease | 34 (9.1) | 12 (11.2) | 22 (8.3) | 0.377 |
| Atrial fibrillation | 9 (2.4) | 3 (2.8) | 6 (2.3) | 0.759 |
| Prior stroke | 127 (34.1) | 39 (36.4) | 88 (33.2) | 0.551 |
| Smoking | 91 (24.5) | 31 (29.0) | 60 (22.6) | 0.355 |
| Drinking | 94 (25.3) | 24 (22.4) | 70 (26.4) | 0.636 |
| Hematoma volume, mL, median (IQR) | 12 (8, 18) | 14 (8, 20) | 12 (8, 16) | 0.102 |
| Hematoma location, n (%) | ||||
| Frontal lobe | 9 (2.4) | 5 (4.7) | 4 (1.5) | 0.072 |
| Parietal lobe | 22 (5.9) | 10 (9.3) | 12 (4.5) | 0.075 |
| Temporal lobe | 34 (9.1) | 9 (8.4) | 25 (9.4) | 0.757 |
| Occipital lobe | 24 (6.5) | 8 (7.5) | 16 (6.0) | 0.609 |
| Basal ganglia | 290 (78.0) | 91 (85.0) | 199 (75.1) | 0.036 |
| Cerebellum | 22 (5.9) | 5 (4.7) | 17 (6.4) | 0.519 |
| Brainstem | 10 (2.7) | 2 (1.9) | 8 (3.0) | 0.535 |
| Concurrent ventricular hemorrhage | 61 (16.4) | 21 (19.6) | 40 (15.1) | 0.285 |
| Hematologic parameters | ||||
| WBC, x109/L, median (IQR) | 7.94 (6.35, 10.04) | 8.55 (6.84, 10.49) | 7.73 (6.11, 9.82) | 0.006 |
| ANC, x109/L, median (IQR) | 5.80 (3.99, 7.70) | 6.95 (5.43, 9.04) | 5.33 (3.50, 7.22) | <0.001 |
| ALC, x109/L, median (IQR) | 1.35 (1.01, 1.70) | 1.17 (0.85, 1.51) | 1.40 (1.09, 1.79) | <0.001 |
| NLR, median (IQR) | 4.14 (2.63, 6.36) | 6.15 (4.22, 9.87) | 3.55 (2.42, 5.89) | <0.001 |
| Neuropsychological function | ||||
| NIHSS score, median (IQR) | 6 (3, 11) | 12 (9, 15) | 5 (3, 8) | <0.001 |
| GCS score, median (IQR) | 15 (15, 15) | 14 (14, 15) | 15 (15, 15) | <0.001 |
| mRS score, median (IQR) | 2 (1, 4) | 4 (3, 4) | 2 (0, 3) | <0.001 |
| BI score, median (IQR) | 90 (20, 100) | 20 (20, 65) | 100 (65, 100) | <0.001 |
| MMSE score, median (IQR) | 25 (24, 26) | 25 (24, 26) | 25 (24, 26) | 0.249 |
Abbreviations: ICH, intracerebral hemorrhage; IQR, interquartile range; WBC, white blood cells; ANC, absolute neutrophil count; ALC, absolute lymphocyte count; NLR, neutrophil-to-lymphocyte ratio; NIHSS, National Institute of Health Stroke Scale; GCS, Glasgow Coma Scale; mRS, modified Rankin Scale; BI, Barthel Index; MMSE, Mini-Mental State Examination.