Table 3.
Outcomes
| Full cohort (n=1035) | ARDS cohort*(n=779) | ||
|---|---|---|---|
| Patient status at study completion | |||
| Discharged alive to home or acute rehabilitation centre | 311 (30%) | 262 (34%) | |
| Discharged alive to long-term acute care centre or unspecified location | 101 (10%) | 79 (10%) | |
| Discharged to another hospital | 176 (17%) | 97 (12%) | |
| Remain in the hospital (discharged from ICU) | 11 (1%) | 10 (1%) | |
| Remain in the ICU | 56 (5%) | 40 (5%) | |
| In-hospital death | 380 (37%) | 291 (37%) | |
| Tracheostomy† | 444 (44%) | 353 (47%) | |
| Select complications‡ | |||
| Seizure | 6 (0·6%) | 5 (0·7%) | |
| CNS infarct | 7 (0·7%) | 5 (0·7%) | |
| CNS haemorrhage | 56 (6%) | 44 (6%) | |
| Haemolysis | 48 (5%) | 37 (5%) | |
| Membrane lung failure | 82 (8%) | 63 (9%) | |
| Pump failure | 8 (0·8%) | 6 (0·8%) | |
| Circuit change | 148 (15%) | 99 (13%) | |
Data are n (%). ARDS=acute respiratory distress syndrome. ECMO=extracorporeal membrane oxygenation. ICU=intensive care unit.
The ARDS cohort were the subset of ECMO-supported patients with COVID-19 who met the following two criteria: (1) classified by the Extracorporeal Life Support Organization data manager as having ARDS, and (2) initial mode of ECMO support was venovenous ECMO.
Full cohort n=1003; ARDS cohort n=756. Only 1003 patients in the full cohort and 756 patients in the ARDS cohort reported whether or not they had a tracheostomy; for the remainder it was missing.
Full cohort n=983; ARDS cohort n=738. Complications were only reported in 983 patients in the full cohort and 738 patients in the ARDS cohort; in the remainder it was missing.