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. 2020 Sep 24;10:15647. doi: 10.1038/s41598-020-73193-y

Table 2.

Inhibition halo (IH) diameter, minimum inhibitory concentration (MIC) and minimum bactericidal concentration (MBC) obtained on treating microorganisms with the essential oils from leaves and flowers of S. hydrangea.

Microorganism Leaves Flowers Antibiotics
Rifampin Gentamicin Nystatin
IH (mm) MIC (µg/mL) MBC (µg/mL) IH (mm) MIC (µg/mL) MBC (µg/mL) IH (mm) MIC (µg/mL) IH (mm) MIC (µg/mL) IH (mm) MIC (µg/mL)
Shigella dysenteriae ND 62.5 62.5 ND 62.5 125 9 ± 0.00b 15.63 17 ± 0.01a 3.90 NA NA
Pseudomonas aeruginosa ND 15.63 >  15.63 >  ND 15.63 >  15.63 >  ND 31.25 20 ± 0.00a 7.81 NA NA
Bacillus subtilis 9.50 ± 0.00 c 250  > 1000 ND 31.25 31.25 19 ± 0.00b 31.25 30 ± 0.02a 3.90 NA NA
Staphylococcus epidermidis 9.50 ± 0.00d 1000 1000 10.67 ± 1.15c 250 250 44 ± 0.01a 1.95 39 ± 0.00b 1.95 NA NA
Escherichia coli ND 1000 1000 ND 31.25 125 10 ± 0.00b 15.63 23 ± 0.02a 31.25 NA NA
Staphylococcus aureus 9.50 ± 0.50 c 500  > 1000 ND 125 125 21 ± 0.01b 31.25 27 ± 0.03a 1.95 NA NA
Klebsiella pneumoniae ND 62.50 62.5 ND 62.5 62.5 8 ± 0.00b 15.63 17 ± 0.03a 3.90 NA NA
Proteus vulgaris ND 250 250 ND 125 125 8 ± 0.00b 15.63 24 ± 0.04a 15.63 NA NA
Salmonella paratyphi-A ND 125 125 ND 62.5 125 8 ± 0.01b 15.63 18 ± 0.01a 3.90 NA NA
Candida albicans ND 250 250 ND 1000 1000 NA NA NA NA 33 ± 0.01a 125
Aspergillu sniger ND  > 2000  > 2000 ND 2000 2000 NA NA NA NA 27 ± 0.00a 31.2
Aspergillus brasiliensis ND  > 2000  > 2000 ND 2000 2000 NA NA NA NA 30 ± 0.01a 31.2

NA indicates no activity and ND indicates not determined. Mean values ± standard deviations of three cultures were reported (n = 3).

Values with different letters are statistically different (Duncan, p ≤ 0.05).