Table 3.
APOE genotypic frequencies distribution in control and all sepsis patients.
| Genotype | Control (n = 699) | All patients (n = 601) | p value | Chi square | Odds ratio (95% CI) |
|---|---|---|---|---|---|
| APOE4+ | 110 (15.7) | 117 (19.5) | 0.077 | 3.121 | 1.294 (0.972–1.724) |
| APOE4− | 589 (84.3) | 484 (80.5) | |||
| E2/E2 | 7 (1.0) | 4 (0.7) | 0.510 | 0.435 | 0.662 (0.193–2.274) |
| E2/E3 | 100 (14.3) | 84 (14.0) | 0.865 | 0.029 | 0.973 (0.712–1.331) |
| E3/E3 | 482 (69.0) | 396 (65.9) | 0.239 | 1.385 | 0.870 (0.689–1.097) |
| E2/E4 | 11 (1.6) | 15 (2.5) | 0.236 | 1.402 | 1.601 (0.730–3.513) |
| E3/E4 | 93 (13.3) | 100 (16.6) | 0.092 | 2.842 | 1.301 (0.958–1.766) |
| E4/E4 | 6 (0.9) | 2 (0.3) | 0.227 | 1.460 | 0.386 (0.078–1.918) |
OR odds ratio, 95% CI 95% confidence interval ratio.