Table 4.
APOE genotypic frequencies distribution in patients with sepsis subtype and septic shock.
| Genotype | Sepsis subtype (n = 341) | Septic shock (n = 260) | p value | Chi square | Odds ratio (95% CI) |
|---|---|---|---|---|---|
| APOE4+ | 56 (16.4) | 61 (23.5) | 0.031 | 4.663 | 1.560 (1.040–2.340) |
| APOE4− | 285 (83.6) | 199 (76.5) | |||
| E2/E2 | 2 (0.6) | 2 (0.8) | 1.000 | 0.000 | 1.314 (0.184–9.390) |
| E2/E3 | 44 (12.9) | 40 (15.4) | 0.385 | 0.755 | 1.227 (0.773–1.949) |
| E3/E3 | 239 (70.1) | 157 (60.4) | 0.013 | 6.180 | 0.651 (0.463–0.914) |
| E2/E4 | 4 (1.2) | 11 (4.2) | 0.017 | 5.668 | 3.722 (1.171–11.826) |
| E3/E4 | 51 (15.0) | 49 (18.8) | 0.205 | 1.610 | 1.321 (0.859–2.031) |
| E4/E4 | 1 (0.3) | 1 (0.4) | 1.000 | 0.000 | 1.313 (0.082–21.087) |
OR odds ratio, 95% CI 95% confidence interval ratio.