Table 3.
The effects of different treatments on the egg load in the S. mansonai infected groups.
| Experimental groups | Subgroups | Intestinal egg load | Hepatic egg load | ||
|---|---|---|---|---|---|
| Mean ± SD | % Reduction | Mean ± SD | % Reduction | ||
| 1. Infected not treated | 38,130 ± 1100 | 0 | 46,880 ± 1132 | 0 | |
| Infected treated groups | |||||
| 2. Curcumin | Cur-1 | 35,000 ± 378 | 8.20 | 33,750 ± 791 | 28.00 |
| Cur-3 | 24,000 ± 586 | 37.05 | 30,880 ± 666 | 34.12 | |
| 3. PZQ | 2675 ± 212 | 92.98*** | 3000 ± 167 | 93.60*** | |
| 4. Curcumin + PZQ | Cur-1 + PZQ | ||||
| Cur-3 + PZQ | 21,750 ± 306 | 42.95 | 21,130 ± 223 | 54.92 | |
| 5. Cur-GNPs | Cur-loaded-1 | 8670 ± 116 | 77.30*** | 9670 ± 58 | 79.40*** |
| Cur-loaded-3 | 8670 ± 306 | 77.26*** | 7570 ± 230 | 83.85*** | |
| 6. Cur-GNPs + PZQ | Cur-loaded-1 + PZQ | ||||
| Cur-loaded-3 + PZQ | 10,000 ± 100 | 73.77*** | 25,000 ± 707 | 46.67 | |
***P < 0.001 vs. the Infected not treated.