Table 2.
The GC-risk related gut microbiota identified by the ROC analysis.
The different bacterial taxa | The original population | The matching population | ||||||
---|---|---|---|---|---|---|---|---|
Relative abundance (%) | Z(P) | AUC (95% CI) | Relative abundance (%) | Z(P) | AUC (95% CI) | |||
Cases (n = 134) | Controls (n = 58) | Cases (n = 44) | Controls (n = 44) | |||||
g_Veillonella | 2.25 ± 3.57 | 0.78 ± 3.76 | 7.409 (0.000) | 0.837 (0.772, 0.902) | 2.18 ± 3.97 | 0.37 ± 1.45 | 5.741 (0.000) | 0.855 (0.773, 0.937) |
s_Streptococcus mitis | 0.37 ± 0.74 | 0.26 ± 1.13 | 5.583 (0.000) | 0.754 (0.679, 0.829) | 0.29 ± 0.52 | 0.33 ± 1.29 | 3.541 (0.000) | 0.719 (0.610, 0.828) |
g_Megasphaera | 0.94 ± 4.29 | 0.03 ± 0.11 | 5.458 (0.000) | 0.743 (0.670, 0.815) | 0.73 ± 3.10 | 0.04 ± 0.13 | 4.097 (0.000) | 0.745 (0.640, 0.849) |
s_Streptococcus salivarius subsp. salivarius | 2.77 ± 3.29 | 1.26 ± 4.14 | 5.231 (0.000) | 0.738 (0.663, 0.813) | 2.79 ± 3.54 | 1.50 ± 4.72 | 3.843 (0.000) | 0.738 (0.633, 0.842) |
s_Bifidobacterium dentium | 0.08 ± 0.23 | 0.02 ± 0.08 | 4.787 (0.000) | 0.705 (0.629, 0.781) | 0.06 ± 0.10 | 0.01 ± 0.06 | 4.238 (0.000) | 0.741 (0.635, 0.848) |
s_Lactobacillus salivarius | 0.92 ± 1.88 | 0.08 ± 0.24 | 4.418 (0.000) | 0.695 (0.621, 0.769) | 0.84 ± 1.77 | 0.06 ± 0.21 | 3.452 (0.001) | 0.705 (0.594, 0.815) |
g_Prevotella 7 | 0.44 ± 1.73 | 0.02 ± 0.10 | 4.591 (0.000) | 0.694 (0.618, 0.771) | 0.30 ± 0.73 | 0.01 ± 0.07 | 4.201 (0.000) | 0.739 (0.635, 0.844) |