Table 2.
Serum concentrations of vitamin D biomarkers according to general characteristics of the adult Brazilian pregnant women studied.∗
| 25(OH)D3 | DBP | PTH | Free 25(OH)D3 | Bioavailable 25(OH)D3 | ||||||
|---|---|---|---|---|---|---|---|---|---|---|
| (nmoL/L) | P † | (mg/L) | P | (pg/mL) | P | (pg/mL) | P | (ng/mL) | P | |
| Gestational period | ||||||||||
| 27–31 wk | 54.4 ± 14.3 | 0.145 | 825 ± 164 | 0.062 | 28.7 ± 13.6 | 0.560 | 1.38 ± 0.40 | 0.679 | 0.40 ± 0.14 | 0.369 |
| 32–36 wk | 49.4 ± 13.1 | 753 ± 146 | 31.5 ± 17.4 | 1.35 ± 0.38 | 0.37 ± 0.11 | |||||
| 37–41 wk | 48.6 ± 14.1 | 760 ± 128 | 28.2 ± 13.3 | 1.30 ± 0.44 | 0.36 ± 0.13 | |||||
| BMI before pregnancy | ||||||||||
| Underweight or normal | 49.5 ± 13.2 | 0.513 | 768 ± 153 | 0.072 | 28.4 ± 13.7 | 0.632 | 1.35 ± 0.42ab | 0.048 | 0.38 ± 0.13 | 0.065 |
| Overweight | 53.3 ± 13.5 | 746 ± 144 | 30.3 ± 19.5 | 1.48 ± 0.42a | 0.42 ± 0.14 | |||||
| Obesity | 51.2 ± 16.1 | 833 ± 130 | 31.6 ± 13.1 | 1.20 ± 0.31b | 0.34 ± 0.96 | |||||
| Skin type | ||||||||||
| Very light or light | 50.3 ± 13.0 | 0.698 | 756 ± 131 | 0.311 | 34.1 ± 18.8 | 0.470 | 1.38 ± 0.43 | 0.877 | 0.38 ± 0.13 | 0.946 |
| Intermediate | 52.6 ± 13.5 | 785 ± 152 | 28.9 ± 16.3 | 1.37 ± 0.37 | 0.39 ± 0.12 | |||||
| Tanned | 51.2 ± 14.5 | 814 ± 179 | 28.2 ± 11.2 | 1.31 ± 0.41 | 0.38 ± 0.13 | |||||
| Brown or dark | 48.5 ± 14.8 | 750 ± 155 | 28.3 ± 13.6 | 1.32 ± 0.43 | 0.37 ± 0.13 | |||||
| Previous pregnancy | ||||||||||
| 0 | 50.1 ± 14.4 | 0.137 | 788 ± 112 | 0.136 | 27.4 ± 15.9 | 0.537 | 1.29 ± 0.36 | 0.136 | 0.37 ± 0.12 | 0.086 |
| 1 | 53.5 ± 14.2 | 774 ± 150 | 30.0 ± 14.3 | 1.43 ± 0.41 | 0.41 ± 0.13 | |||||
| ≥2 | 47.4 ± 12.5 | 772 ± 181 | 31.2 ± 14.8 | 1.27 ± 0.41 | 0.35 ± 0.13 | |||||
| Gestational weight gain | ||||||||||
| <0.30 kg/wk | 50.2 ± 14.4 | 0.675 | 762 ± 133 | 0.238 | 28.6 ± 15.8 | 0.499 | 1.33 ± 0.41 | 0.792 | 0.38 ± 0.13 | 0.915 |
| ≥0.30 kg/wk | 51.3 ± 13.6 | 795 ± 162 | 30.5 ± 13.9 | 1.35 ± 0.40 | 0.38 ± 0.12 | |||||
| Season | ||||||||||
| Spring | 58.7 ± 13.1a | <0.001 | 841 ± 160a | 0.019 | 31.1 ± 12.7 | 0.660 | 1.45 ± 0.38a | 0.014 | 0.42 ± 0.12a | 0.002 |
| Summer | 52.5 ± 13.4ab | 761 ± 159ab | 26.7 ± 15.0 | 1.42 ± 0.43ab | 041 ± 0.13ab | |||||
| Autumn | 48.4 ± 13.8bc | 757 ± 120ab | 29.1 ± 16.5 | 1.31 ± 0.41ab | 0.36 ± 0.12abc | |||||
| Winter | 41.1 ± 8.6c | 735 ± 126b | 30.6 ± 16.2 | 1.15 ± 0.33b | 0.31 ± 0.99c | |||||
∗Values are unadjusted mean ± standard deviation. P†Values for unadjusted least square means (LSD) post hoc test. For each exposure variable, different superscript letters indicate significant difference between categories on the outcome variable (25(OH)D3, DBP, PTH, free 25(OH)D3, and bioavailable 25(OH)D3).