Fig. 1.

Pediatric buccal DNA methylation age accurately predicted chronological age. (A) The training data (datasets 1 through 7) was used in an elastic net regression for selection of 94 age-related CpG sites. Estimated age (PedBE age) (y axis) versus chronological age (x axis). (B) The test data (datasets 8 through 11) was to independently assess the PedBE clock (r = 0.98, test error = 0.35 y). Each data point represents an individual, with the color indicating the corresponding dataset. Solid black and dashed lines denote the linear regression and perfect correlation lines, respectively.