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Changes in the amino acid pattern alter the conformational ensemble of PNt. Log-log and dimensionless Kratky plots from analysis of SAXS profiles of PNt and swap variants with (A and B) altered hydrophobic clustering or (C and D) altered charge patterning in (A and B) 0 M or (B and D) 2 M Gdn. Rg and ν were extracted from the fit to the MFF (3).
