Table 1.

Clinical and Sociodemographic characteristics of the sample.

	Controls	HD	HD-ND	HD-Dem	P
Age	45.9 ± 8	51.8 ± 12	50.85 ± 11	53.2 ± 14	a0.096; b0.156; c0.102; d0.590
Gender (f/m)	4/11	23/12	12/8	11/4	a0.012; b0.052; c0.013; d0.324
Education	12.3 ± 2	11.5 ± 4	11.2 ± 5	12 ± 4	a0.376; b0.346; c0.778; d0.615
CAG	–	43.7 ± 3	43.3 ± 3	44 ± 3	d0.424
DBS1	–	492 ± 84	469 ± 80	523 ± 83	d0.061
UHDRS-TMS2	–	28.5 ± 17	22.5 ± 18	37.2 ± 11	d < 0.01
TFC3	–	11.2 ± 2	12.1 ± 1	10 ± 2	d < 0.01
PD-CRS total score	106.7 ± 10.7	70.17 ± 21	84.3 ± 15	51.2 ± 10	a < 0.001; b < 0.001; c < 0.001; d < 0.001
UHDRS cogscore	–	170.2 ± 78	212 ± 72	114 ± 47	d < 0.001
MMSE	29.3 ± 0.8	25.2 ± 3.8	27.8 ± 1.8	21.6 ± 2.6	a < 0.001; b<0.005; c < 0.001; d < 0.001

¹Disease burden score; ²Unified Huntington’s disease rating scale – Total motor score; ³Total functional capacity.

^aHC vs HD

^bHC vs HD-ND

^cHC vs HD-Dem

^dHD-ND vs HD-Dem