Table 2.
Univariate COX regression analysis of the prognostic factors of special breast cancer.
| Variables | Overall survival |
|
|---|---|---|
| HR (95%CI) | P value | |
| Age | <0.0001 | |
| ≤40 years | Reference | |
| 40–65 years | 1.40 (0.98–2.00) | 0.061 |
| ≥65 years | 3.62 (2.56–5.14) | <0.0001 |
| Race | <0.0001 | |
| White | Reference | |
| Black | 1.29 (1.12–1.49) | <0.0001 |
| Other | 0.70 (0.56–1.87) | 0.001 |
| Grade | <0.0001 | |
| Grade1 | Reference | |
| Grade2 | 1.07 (0.93–1.22) | 0.364 |
| Grade3 | 1.70 (1.48–2.05) | <0.0001 |
| Grade4 | 1.51 (0.96–2.38) | 0.078 |
| T stage | <0.0001 | |
| T0 | Reference | |
| T1 | 8.94 (0.09–11.95) | 0.734 |
| T2 | 9.46 (0.40–11.68) | 0.731 |
| T3 | 14.90 (0.42–22.66) | 0.705 |
| T4 | 18.55 (0.73–33.11) | 0.693 |
| N stage | 0.026 | |
| N0 | Reference | |
| N1mi | 1.09 (0.90–1.33) | 0.375 |
| N1 | 1.10 (0.66–1.84) | 0.713 |
| N2 | 1.44 (1.03–2.00) | 0.033 |
| N3 | 1.28 (0.94–1.73) | 0.119 |
| M stage | <0.0001 | |
| M0 | Reference | |
| M1 | 5.08 (3.32–7.78) | <0.0001 |
| pTNM | <0.0001 | |
| I | Reference | |
| II | 1.68 (1.22–2.31) | 0.001 |
| III | 2.63 (1.71–4.04) | <0.0001 |
| IV | 4.18 (2.96–8.34) | <0.0001 |
| Subtype | <0.0001 | |
| LuminalA | Reference | |
| Luminal | 0.79 (0.60–1.03) | 0.078 |
| HER2 | 0.96 (0.67–1.37) | 0.812 |
| TN | 1.69 (1.46–1.97) | <0.0001 |
| Surgery | <0.0001 | |
| No | Reference | |
| Yes | 0.34 (0.28–0.41) | <0.0001 |
| Radiotherapy | <0.0001 | |
| No/Unknown | Reference | |
| Yes | 0.51 (0.46–0.58) | <0.0001 |
| Chemotherapy | <0.0001 | |
| No/Unknown | Reference | |
| Yes | 0.61 (0.52–0.70) | <0.0001 |