Distribution of genomic islands (GIs), prophages, and integrative conjugative element (ICE) in the genome of V. cholerae clinical isolates. Each of the genetic elements except prophages is linked with different mobility functions like integrase and repeat sequences. GC contents of the acquired genetic elements are also distinct compared to the core genome. VPI-1, Vibrio pathogenicity island-1; VPI-2, Vibrio pathogenicity island-2; VSP-1, Vibrio seventh pandemic island-1; VSP-2, Vibrio seventh pandemic island-2; int, integrase.