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. 2020 Sep;45(5):341–351. doi: 10.30476/ijms.2020.72514.0

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Copyright: © Iranian Journal of Medical Sciences

This is an open-access article distributed under the terms of the Creative Commons Attribution-Noncommercial-Share Alike 4.0 Unported, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

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Evaluation of biochemical changes in colon tissues is shown in this figure. (A) Myeloperoxidase activity was reduced after cell injection. Both the adherent and non-adherent mesenchymal stem cells down-regulated myeloperoxidase activity in a significant manner compared with the control colitis group. (B) The levels of nitric oxide activity were down-regulated in the gut tissue of the treatment groups. There was no significant regression between the groups with adherent and non-adherent mesenchymal stem cells. (C) Administration of adherent mesenchymal stem cells and non-adherent mesenchymal stem cells markedly reduced the elevated lipid peroxidation. (D) The total protein concentration in colonic tissues differed in the treated groups. There was a significant difference between the adherent and non-adherent mesenchymal stem cells groups; nevertheless, both markedly increased the protein level compared with the control colitis group (*P<0.001 versus control positive rats).