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. 2020 Sep 25;3(9):e2021892. doi: 10.1001/jamanetworkopen.2020.21892

Table 4. Hospitalization, ICU Admission, Use of Mechanical Ventilator, and Death Among Patients With Coronavirus Disease 2019a.

Factor Hospitalization ICU admission Mechanical ventilator In-hospital death
OR (95% CI)b P value OR (95% CI)b P value OR (95% CI)b P value OR (95% CI)b P value
Patient race and socioeconomic status
Black race 1.85 (1.0-3.67) .04 1.52 (0.75-3.07) .24 1.02 (0.37-2.80) .96 1.43 (0.14-14.1) .31
Enrolled in Medicaid 3.84 (1.20-12.3) .02 3.58 (1.08-11.8) .04 2.05 (0.28-14.68) .47 5.33 (014-19.92) .36
Interaction of race × poverty status 0.35 (0.09-1.43) .09 0.15 (0.03-0.70) .02 0.13 (0.01-1.47) .10 0.02 (0.001-2.44) .11
Patient demographic characteristics
Aged ≥60 y v <60 y 1.78 (1.00-3.18) .05 1.95 (1.01-3.83) .05 1.74 (0.67-4.59) .26 22.79 (3.38-53.81) .001
Men vs women 1.22 (0.70-2.10) .48 1.03 (0.59-1.83) .90 0.44 (0.16-1.15) .10 0.05 (0.005-0.43) .06
Comorbidities
3 1 [Reference] NA 1 [Reference] NA 1 [Reference] NA 1 [Reference] NA
0 0.43 (0.19-0.98) .04 0.36 (0.14-0.91) .03 0.22 (0.05-0.830 .02 0.05 (0.005-0.39) .005
1-2 0.51 (0.28-0.97) .04 0.57 (0.29-1.12) .10 0.25 (0.08-0.70) .009 0.01 (0.006-0.16) .001
BMI 0.99 (0.71-2.10) .55 1.03 (0.99-1.08) .90 1.06 (1.02-1.09) .003 1.19 (1.05-1.35) .006
History of smoking or current smoking vs no smoking 1.38 (0.79-2.43) .37 2.14 (1.15-3.98) .01 4.24 (1.54-8.61) .001 7.15 (0.55-9.22) .13
Symptoms at testing
Fever 2.56 (1.49-4.38) .001 1.87 (1.08-3.46) .05 2.68 (0.99-7.37) .06 0.73 (0.15-3.48) .70
Cough 0.44 (0.24-0.81) .008 0.65 (0.31-1.34) .24 0.24 (0.07-0.79) .02 0.04 (0.005-0.33) .003
Shortness of breath 3.44 (2.03-5.84) .001 4.50 (2.31-8.74) .001 9.86 (2.82-34.39) .001 10.67 (1.52-25.54) .02
Diarrhea, nausea, vomiting, or abdominal pain 1.25 (0.69-2.29) .28 1.16 (0.60-2.25) .65 1.00 (0.31-3.17) .99 0.43 (0.09-2.04) .21
Other symptoms 1.41 (0.75-2.64) .45 1.36 (0.68-2.25) .38 3.10 (0.53-18.02) .21 3.15 (1.10-8.94) .03

Abbreviations: BMI, body mass index; ICU, intensive care unit; OR, odds ratio.

a

Sample size was 369 patients with coronavirus disease 2019 for hospitalization and ICU use; 311 patients with coronavirus disease 2019 for mechanical ventilator, after excluding persons with missing BMI due to collinearity; and 116 hospitalized patients with coronavirus disease 2019 for in-hospital mortality.

b

The ORs and 95% CIs were obtained from models estimated using a generalized estimating equation logit specification that adjusts for clustering at the zip code–level of patients’ residence. All models also include a constant term and an indicator for missing BMI.