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. 2020 Sep 25;20:465. doi: 10.1186/s12935-020-01493-4

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© The Author(s) 2020

Open AccessThis article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated in a credit line to the data.

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Fig. 2 — Circ_002117 is downregulated in gastric cancer tissues and cells. a RT-qPCR determination of circ_002117 expression in gastric cancer and adjacent normal tissues (N = 87). b Circ_002117 expression in differential malignant grade gastric cancers. c Correlation between circ_002117 and overall survival rate of gastric cancer patients. d RT-qPCR determination of circ_002117 expression in normal gastric epithelial cells and gastric cancer cell lines. *p < 0.05 vs. adjacent normal tissues or patients at I, II, III. ^#p < 0.05 vs. GES-1. Data are shown as the mean ± standard deviation. Data between two groups were analyzed unpaired t-test. Data among multiple groups was analyzed by Tukey’s test-corrected ANOVA. The experiment was repeated in triplicate