Table 6.
Associations of diabetes and poor adherence to inhalers with COPD outcomes
Diabetesa | Poor adherencea | |||
---|---|---|---|---|
COPD outcome | OR (95% CI) | P-value | OR (95% CI) | P-value |
CAT ≥ 10 | 0.49 (0.05–4.50) | 0.531 | 4.86 (1.61–14.69) | 0.005 |
mMRC ≥ 2 | 0.41 (0.15–1.21) | 0.082 | 2.93 (1.51–5.71) | 0.002 |
≥ 2 Exacerbations | 0.47 (0.17–1.31) | 0.151 | 4.68 (1.51–4.44) | 0.007 |
GOLD 2019 – C&D CAT based |
2.83 (1.04–7.71) | 0.041⁋ | 3.13 (1.49–8.53) | 0.026 |
GOLD 2019 – C&D mMRC based |
2.83 (1.04–7.72) | 0.042⁋ | 3.35 (1.24–9.09) | 0.017 |
aMultivariate logistic regression models including both predictors adjusted for gender, age and smoking status. Bold faceted text indicates P-values< 0.05. ⁋ P-value> 0.05 when adding occupational status into the model. OR Odds ratio, COPD Chronic obstructive pulmonary disease, GOLD 2019 Global Initiative for Obstructive Lung Disease 2019 Guidelines, CAT Chronic Obstructive Pulmonary Disease Assessment Test, mMRC Modified Medical Research Council Dyspnoea Scale