Table 2.
Serum angiogenic and inflammatory factors according to clinicopathological features in type 1 endometrial cancer patients
| N (%) | VEGF-A (pg/ml) | P-value | Ang-2 (pg/ml) | P-value | CRP (μg/ml) | P-value | |
|---|---|---|---|---|---|---|---|
| Mean (±SD) | Mean (±SD) | Mean (±SD) | |||||
| Total | 176 (100) | ||||||
| Age (years) | |||||||
| ≤ 60 | 119 (67.6) | 414 (398) | 0.632 | 2012 (891) | 0.005 | 3.61 (2.68) | 0.01 |
| > 60 | 57 (32.4) | 391 (370) | 2948 (1246) | 4.98 (3.29) | |||
| FIGO stage | |||||||
| I-II | 154 (87.5) | 347 (221) | 0.061 | 2212 (1372) | 0.042 | 3.46 (2.97) | < 0.001 |
| III-IV | 22 (12.5) | 432 (443) | 2968 (1314) | 6.92 (3.17) | |||
| Lymphatic vascular space invasion | |||||||
| Yes | 62 (35.2) | 453 (312) | 0.013 | 3102 (1652) | < 0.001 | 5.11 (3.09) | 0.114 |
| No | 114 (64.8) | 349 (305) | 2451 (1232) | 4.32 (3.39) | |||
| Myometrial invasion | |||||||
| < 50% | 79 (44.9) | 316 (181) | 0.002 | 2183 (1386) | 0.009 | 3.09 (2.97) | < 0.001 |
| ≥ 50% | 97 (55.1) | 411 (371) | 2953 (1216) | 5.11 (3.28) | |||
| Histological grade | |||||||
| G1 | 105 (59.7) | 392 (402) | 0.125 | 2562 (985) | 0.135 | 2.54 (1.98) | 0.012 |
| G2 | 71 (40.3) | 375 (328) | 2746 (1134) | 4.16 (2.97) | |||