Table 3.
Obesity-related factors according to clinicopathological features in type 1 endometrial cancers patients
| N (%) | Adiponectin (ng/ml) | P-value | IGF-1 (ng/ml) | P-value | Insulin (μU/ml) | P-value | C-peptide (ng/ml) | P-value | BMI | P-value | |
|---|---|---|---|---|---|---|---|---|---|---|---|
| Mean (±SD) | Mean (±SD) | Mean (±SD) | Mean (±SD) | Mean (±SD) | |||||||
| Total | 176 (100) | ||||||||||
| Age (years) | |||||||||||
| ≤ 60 | 119 (67.6) | 6791 (4132) | 0.001 | 98.41 (26.84) | 0.082 | 18.43 (22.59) | 0.132 | 4.19 (3.45) | 0.392 | 29.42 (4.21) | 0.001 |
| > 60 | 57 (32.4) | 8154 (5321) | 95.35 (29.87) | 14.98 (24.78) | 4.93 (3.74) | 27.14 (5.16) | |||||
| FIGO stage | |||||||||||
| I-II | 154 (87.5) | 8632 (6244) | 0.645 | 96.26 (35.84) | 0.458 | 13.92 (17.92) | 0.747 | 4.58 (3.64) | 0.793 | 27.24 (5.26) | 0.893 |
| III-IV | 22 (12.5) | 8754 (5768) | 87.82 (32.85) | 14.12 (20.24) | 4.78 (3.89) | 27.92 (4.92) | |||||
| Lymphatic vascular space invasion | |||||||||||
| Yes | 62 (35.2) | 8132 (5948) | 0.821 | 91.21 (36.14) | 0.452 | 16.82 (24.87) | 0.604 | 4.73 (3.68) | 0.894 | 27.42 (5.61) | 0.793 |
| No | 114 64.8) | 8241 (6005) | 93.46 (33.86) | 14.93(22.64) | 4.81 (3.76) | 27.29 (5.11) | |||||
| Myometrial invasion | |||||||||||
| < 50% | 79 (44.9) | 8642 (6391) | 0.729 | 94.18 (37.25) | 0.864 | 12.56 (16.24) | 0.151 | 4.45 (3.51) | 0.934 | 27.56 (7.29) | 0.391 |
| ≥ 50% | 97 (55.1) | 8294 (5943) | 92.16 (34.91) | 14.95 (24.62) | 4.65 (3.14) | 26.98 (4.73) | |||||
| Histological grade | |||||||||||
| G1 | 105 59.7) | 9134 (7424) | 0.693 | 91.16 (27.23) | 0.614 | 12.48 (14.68) | 0.534 | 3.87 (2.32) | 0.384 | 26.72 (5.72) | 0.123 |
| G2 | 71 (40.3) | 9251 (5842) | 97.37 (37.51) | 15.96 (19.44) | 4.62 (3.64) | 26.98 (4.49) | |||||