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. 2020 Sep 25;19:148. doi: 10.1186/s12933-020-01127-z

Table 4.

Multiple Regression Analysis of the Change in HRV for the Empagliflozin Group

Secondary evaluation items Single regression Multiple regression
Regression coefficient P Partial regression coefficient 95% confidence interval P
SDANN
 Systolic blood pressure 0.860 < 0.001 1.235 0.774–1.697 < 0.001
 Hematocrit 0.115 0.447
r-MSSD
 Maximum CK 0.003 0.01
 Hematocrit 0.188 0.212
HF
 Maximum CK 0.421 0.002
 Hematocrit 0.174 0.248
LF
 Systolic blood pressure 36.859 0.02
 Hematocrit 0.146 0.334

SDANN, Standard deviation of all 5 min mean normal RR intervals; r-MSSD, Square root of the mean of the sum of the squares of differences between adjacent RR intervals; HF, high-frequency power; LF, low-frequency power; CK, creatine kinase