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. 2020 Sep 25;11:4858. doi: 10.1038/s41467-020-18640-0

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© The Author(s) 2020, corrected publication 2022

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/.

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Fig. 7 — a Chemotherapy response stratified by patient groups of high genomic instability (HGI) or low genomic instability (LGI). b Integration of genomic, transcriptomic and proteomic data for all patients with genomic data available and a gene expression subtype assigned (n = 121), stratified by high and low genomic instability. c Chemotherapy response for patients with Ba/Sq gene expression subtype and patients with non-Ba/Sq gene expression subtype (i.e., LumP, LumU, NE-like or Stroma-rich). d Overview of odds ratios (OR) calculated for molecular and clinical features for all patients (black), NAC (green) and first-line treated patients (yellow). Continuous variables were dichotomized based on the median and high vs. low is presented. Dots indicate odds ratios and horizontal lines show 95% confidence intervals (CI). Open lines indicate that the full range of the 95% CI is not shown. Asterisks denote p-values below 0.05. Currency signs denote p-values below 0.05 in a logistic regression model using continuous data. e Likelihood of cisplatin-based chemotherapy response stratified by genomic instability and gene expression subtypes. P-values were calculated using a chi-square test. Source data are provided as a Source data file.