Figure - PMC

Skip to main content

An official website of the United States government

Here's how you know

Here's how you know

Official websites use .gov
A .gov website belongs to an official government organization in the United States.

Secure .gov websites use HTTPS
A lock ( ) or https:// means you've safely connected to the .gov website. Share sensitive information only on official, secure websites.

View full-text article in PMC

. 2020 Sep 25;11:4871. doi: 10.1038/s41467-020-18715-y

Search in PMC
Search in PubMed
View in NLM Catalog
Add to search

© The Author(s) 2020

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/.

PMC Copyright notice

Fig. 4 — a Schematic showing the all-in-one AAV construct driving the expression of the microABE I744 via an SCP1 minimal promoter and a hU6 promoter for the sgRNA component, with example aligned reads from 7m8-AAV vector and its corresponding plasmid, as well as (b) AAV-DJ packaged vector and its corresponding plasmid. c Percentage of A-to-G conversions are presented as an average of three technical replicates, for either the AAV-7m8 or AAV-DJ serotypes, in HEK293A-YFP cells. Source data are available in the Source data file.