Table 1.
Demographic and clinical profile of HDGEC and HC participants
| HDGEC = 42 | Control = 36 | P/χ2 value | ||
|---|---|---|---|---|
| Gender | M:F | 22:20 | 15:21 | 0.345 |
| Age (years) | M (SD) | 50.16 (12.14) | 50.55 (13.90) | 0.948 |
| Range | 26–75 | 24–69 | ||
| UHDRS–TMS | M (SD) | 9.21 (12.71) | ||
| Range | 0–41 | |||
| UHDRS–TFC | M (SD) | 10.90 (2.64) | ||
| Range | 6–13 | |||
| Disease duration | M (SD) | 5.06 (3.23) | ||
| (years after diagnosis) | Range | 1–13 | ||
| CAG length | M (SD) | 41.26 (1.80) | ||
| Range | 38–46 | |||
| CAPS | M (SD) | 0.88 (0.25) | ||
| Range | 0.32–1.40 | |||
| Years of education | M (SD) | 14.61 (2.94) | 14.83 (3.20) | 0.461 |
| Range | 8–21 | 9–23 | ||
| Estimated IQ | M (SD) | 104.04 (6.99) | 106.14 (6.43) | 0.171 |
| Range | 87–115 | 89–117 | ||
| GIHAQ | M (SD) | 21.47 (25.44) | 15.81 (21.33) | 0.294 |
| Range | 0–119 | 0–116 | ||
| CESD-R | M (SD) | 10.92 (10.45) | 7.06 (7.75) | 0.071 |
| Range | 0–43 | 0–31 |
CAPS: scaled CAG-age product score (for premanifest HDGECs only); estimated intelligence quotient (IQ) calculated by Wechsler Test of Adult Reading; CESD-R: Center for Epidemiologic Studies Depression Scale-Revised (range: 0–80); F: female; GIHAQ: Gastrointestinal Health Appraisal Questionnaire (range: 0–280); M: male; TFC: Total Functional Capacity (range: 0–13); disease duration is for manifest HDGECs only; TMS: Total Motor Score (range: 0–124). P/χ2 value signifies probability value between groups, using independent samples t-tests or Chi-squared test (χ2 for gender).