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. 2020 Aug 21;2(2):fcaa133. doi: 10.1093/braincomms/fcaa133

Figure 1.

Figure 1

Mice lacking one Tbk1 allele do not show morphological or behavioural changes. (A) Photographs showing a wt mouse and a Tbk1+/− sibling. (B) Weight development is similar in Tbk1+/− mice and wt siblings during the study period. (C) Tbk1+/− mice and wt siblings show a similar performance in the rotarod test during the study period. (D) Tbk1+/− and wt mice show similar lengths of stay in the centre of the open field arena. (E) Spontaneous alternation performance value does not differ between Tbk1+/− and wt mice in the Y-maze test. (F) The lengths of stay in the social areas in the three-chamber test is not different between Tbk1+/− and wt mice. (G) Tbk1+/− and wt mice do not display premature lethality during the study period. N = 18–20 males per genotype. Data in B–F are shown as mean ± SEM and were analysed by paired t-test. Kaplan–Meier plot was analysed using the Log-rank (Mantel–Cox) test.