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. 2020 Sep 22;13:9377–9388. doi: 10.2147/OTT.S261700

Figure 8.

Figure 8

Paclitaxel regulated HCC tumorigenesis by modulating circ-BIRC6/miR-877-5p/YWHAZ axis. (A) Western blot assay was conducted to measure the protein expression of YWHAZ in control cells or cells (Huh-7 and Hep3B) transfected with si-NC, si-circ-BIRC6, si-circ-BIRC6 + anti-miR-NC, or si-circ-BIRC6 + anti-miR-877-5p. (B) The protein level of YWHAZ was detected by Western blot analysis in control cells or cells (Huh-7 and Hep3B) treated with paclitaxel, paclitaxel + pcDNA, paclitaxel + circ-BIRC6. (C) Paclitaxel repressed hepatocellular carcinoma tumorigenesis by regulating the circ-BIRC6/miR-877-5p/YWHAZ axis. *P<0.05.