Table 5:

Behavioral analysis of Fmr1 KO and WT mice during recall tests. All statistics here are comparisons between naïve and fear conditioned mice of the same genotype. Although Fmr1 KO mice show similar shifts in behavior after fear conditioning, these changes are consistently less pronounced than in WT mice.

	% (r effect size [95% CI])
	WT			Fmr1 KO
Tone
Non-Fear	Naive	Fear Conditioned		Naive	Fear Conditioned
Rearing	31.1	8.8	***(0.74 [0.89 – 0.47])	48.7	16.6	*** (0.85 [0.93 – 0.66])
Motion	33.3	15	** (0.68 [0.85 – 0.36])	24.7	24.7
Fear
Scanning	18.3	35.5	** (0.69 [0.86 – 0.38])	11.7	28.2	** (0.67 [0.85 – 0.35])
Freezing	5	31.1	*** (0.82 [0.92 – 0.61])	3	16.1	* (0.58 [0.81 – 0.22])
Context
Non-Fear	Naive	Fear Conditioned		Naive	Fear Conditioned
Rearing	20.5	2.7	*(0.59 [0.81 – 0.23])	24.1	11.1
Motion	34.4	7.7	*** (0.74 [0.89 – 0.47])	40.1	24.7	* (0.54 [0.78 – 0.15])
Fear
Scanning	29.4	48.3	** (0.65 [0.84 – 0.32])	24.7	31.3
Freezing	7.7	26.6	** (0.65 [0.84 – 0.32])	4.3	18.6	* (0.54 [078 – 0.16])
Context + Tone
Non-Fear	Naive	Fear Conditioned		Naive	Fear Conditioned
Rearing	26.1	0.0	** (0.69 [0.86 – 0.38])	27.2	13.1
Motion	33.3	2.8	***(0.75 [0.89 – 0.47])	31.5	14.6	*(0.52 [0.77 – .13])
Fear
Scanning	30.5	36.1	ns (0.22 [0.59 – (−0.22)])	26.5	33.8
Freezing	57.7	3.8	*** (0.91 [0.96 – 0.79])	4.9	26.2	**(0.65 [0.84 – 0.32])

^*( p = 0.05

^**p = 0.01

^***p < 0.001)