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. 2020 Sep 22;13:9333–9348. doi: 10.2147/OTT.S244879

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© 2020 Wang et al.

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LINC01116 expression is significantly up-regulated in cisplatin-resistant A549/DDP cells as compared to that in parental A549 cells. (A) Morphologies of A549 and A549/DDP cells (× 20). (B) qPCR assay detected higher LINC01116 expression in cisplatin-resistant LAD specimens than in non-resistant specimens. (C) qPCR assay detected higher LINC01116 expression in A549/DDP cells than in A549 cells. (D) The IC₅₀ value of cisplatin against A549/DDP cells is significantly greater than that against A549 cells. All experiments are repeated in triplicated, and data are shown as mean ± SE. *P < 0.05, **P < 0.01.