Table 3.
Astrocytes | Endothelial | Ependymal | Microglia | Neurons1 | Neurons2 | Schwann cells | OM | OPC | VLMC | unknown | |
---|---|---|---|---|---|---|---|---|---|---|---|
DEGs consistent across cell types | |||||||||||
Sod1 | 2.51 | 2.43 | 2.41 | 1.62 | 2.78 | 2.27 | 3.11 | 3.34 | 2.14 | 2.41 | 2.04 |
Malat1 | −0.76 | −0.25 | – | −0.27 | −0.24 | – | −0.75 | −0.33 | −0.41 | −0.28 | −0.48 |
mt-Cytb | 0.42 | 0.28 | − | 0.54 | 0.78 | 0.5 | 0.51 | 0.27 | – | 0.84 | – |
mt-Rnr2 | −0.44 | −0.15 | −0.97 | −0.44 | – | – | – | −0.52 | −0.46 | – | −0.53 |
Gm26924 | −0.53 | −0.31 | – | −0.55 | −0.74 | – | – | −0.58 | −0.44 | – | −0.62 |
Ubb | 0.67 | 0.31 | – | – | 0.95 | – | – | 0.39 | 0.32 | – | 0.86 |
Grid2 | – | 1.1 | 1.58 | – | – | 1.82 | 1.62 | 1.08 | – | – | – |
Lrrc4c | −1.2 | – | – | – | −0.86 | – | −0.98 | −0.35 | −0.59 | – | −0.96 |
Fth1 | 0.37 | 0.35 | – | – | – | – | 0.76 | 0.32 | 0.66 | – | 0.71 |
Rpl26 | 0.38 | 1.24 | – | – | 1.39 | – | – | 0.62 | 1.16 | – | 0.74 |
Rora | −0.71 | – | – | – | −0.63 | 1.39 | – | – | −0.72 | – | – |
Tmtc2 | −0.37 | −0.36 | – | – | −0.69 | – | – | −0.42 | – | – | −0.87 |
Plxdc2 | −0.26 | – | – | −0.39 | −0.69 | – | −1.02 | −0.42 | – | – | – |
Dst | −0.3 | −0.31 | – | – | – | −0.84 | – | −0.3 | – | – | −0.63 |
Diap2 | −0.3 | −0.49 | – | −0.71 | −0.59 | – | – | −0.28 | – | – | – |
Klf7 | −0.25 | – | – | −0.79 | −0.59 | −0.8 | −0.57 | – | – | – | – |
Mt1 | 0.94 | – | – | – | – | – | 0.45 | 0.47 | – | 1.55 | 0.71 |
Dbi | 0.9 | – | – | – | 1.44 | – | 1.08 | 0.24 | 0.47 | – | – |
mt-Rnr1 | 0.32 | 0.36 | – | – | – | 1.04 | 0.6 | – | – | – | – |
mt-Nd4 | 0.24 | 0.32 | – | – | – | 0.46 | – | 0.23 | – | 0.64 | – |
H3f3b | 0.37 | 0.19 | – | 0.45 | – | – | – | 0.29 | – | – | 1.07 |
Cell type specific DEGs | |||||||||||
Cyp26b1 | −0.90 | – | – | – | – | – | – | – | – | – | – |
Gbp4 | – | −0.54 | – | – | – | – | – | – | – | – | – |
Ier3ip1 | – | – | 1.81 | – | – | – | – | – | – | – | – |
Cd74 | – | – | – | −1.43 | – | – | – | – | – | – | – |
Psmd7 | – | – | – | – | 1.12 | – | – | – | – | – | – |
Rgs4 | – | – | – | – | – | −0.91 | – | – | – | – | – |
Fopnl | – | – | – | – | – | – | −0.72 | – | – | – | – |
Cldn11 | – | – | – | – | – | – | – | 0.25 | – | – | – |
Mmp16 | – | – | – | – | – | – | – | – | −0.48 | – | – |
Dcaf7 | – | – | – | – | – | – | – | – | – | −1.21 | – |
Mmd2 | – | – | – | – | – | – | – | – | – | – | −1.55 |