Table 2.

Characteristics of tumors

GBM1	RRBS ID	MI	MVP	Necrosis	Cell	TIL
15043	1	36	Yes	None	Astrocytic	Moderate
9501	2	2	Yes	Extensive with palisade	Astrocytic	Moderate
15916	4	10	Yes	None	Astrocytic	None
9886	5	91	Yes	Extensive	Astrocytic	None
3094	6	120	Yes	Extensive	Astrocytic	Dense
5526	7	20	Yes	Extensive	Astrocytic	Sparse
13501	8	13	Yes	Extensive	Epithelioid	Sparse
12732	9	2	Yes	Extensive with palisade	Astrocytic	Moderate
17578	10	0	No	Extensive	Astrocytic	Dense
15466	11	18	Yes	Extensive	Astrocytic	Dense
10379	12	30	Yes	Extensive	Small cell	Dense
14561	13	36	Yes	Extensive with palisade	Astrocytic	Sparse
2525	14	38	Yes	Extensive with palisade	Astrocytic	Sparse
14642	15	78	Yes	Extensive with palisade	Small cell	Dense
5693	16	42	Yes	Extensive with palisade	Astrocytic	Sparse
7183	17	44	Yes	Extensive with palisade	Astrocytic	Sparse
6795	18	15	Yes	Extensive	Astrocytic	Sparse
16189	19	24	No	None	Small cell	Sparse
8117	20	25	Yes	None	Astrocytic	Dense
3997	21	12	Yes	Palisade	Astrocytic	Sparse
10776	23	32	Yes	Extensive	Astrocytic	Sparse
13956	24	32	Yes	Extensive	Astrocytic	Sparse

GBM2	RRBS ID	MI	MVP	Necrosis	Cell	TIL
9849	R1	100	Yes	Extensive with palisade	Small cell	Sparse
3624	R2	2	No	None	Astrocytic	Dense
9527	R4	32	Yes	Extensive with palisade	Small cell	None
15289	R5	94	Yes	Extensive	Astrocytic	Sparse
15302	R6	4	No	Extensive	Astrocytic	Sparse
13808	R7	21	No	None	Astrocytic	Sparse
9614	R8	20	No	Extensive with palisade	Epithelioid	Sparse
17440	R9	14	No	Extensive	Astrocytic	Sparse
7779	R10	50	Yes	Palisade	Astrocytic	Moderate
16534	R11	14	Yes	Extensive	Astrocytic	Dense
7536	R12	62	Yes	Palisade	Astrocytic	Dense
2315	R13	36	Yes	Palisade	Astrocytic	Sparse
1365	R14	40	Yes	None	Astrocytic	Dense
7990	R15	16	Yes	Extensive with palisade	Small cell	Dense
612	R16	12	Yes	Extensive with palisade	Astrocytic	Dense
11956	R17	22	Yes	Palisade	Astrocytic	Sparse
17545	R18	18	No	Extensive with palisade	Astrocytic	Sparse
16742	R19	18	No	Extensive with palisade	Small cell	Sparse
2908	R20	20	Yes	Palisade	Astrocytic	None
5120	R21	18	Yes	Extensive with palisade	Astrocytic	Sparse
2168	R23	10	No	None	Small cell	Dense
12107	R24	16	No	Palisade	Astrocytic	Dense

This table summarizes histopathological characteristics of GBM1 and GBM2. Histological parameters were assessed by manual eyeballing using low microscopic magnification (100x) and semiquantitative evaluation criteria published previously (Tompa et al. 2018). In statistical analyses, semiquantitative determinants were replaced by numerical values: e.g. TIL: no = 0, sparse = 1, moderate = 2, dense = 3

MI mitotic index (number of mitoses per 10 high power fields), MVP microvascular proliferation, TIL tumor infiltrating lymphocytes