Table 4.
Effects of A. digitata extract on blood lipid profile of hypertensive rats.
Normotensive control | Hypertensive ctrl | LN + captopril | LN + AD100 | LN + AD200 | |
---|---|---|---|---|---|
Total cholesterol (mg/dL) | 65.24 ± 1.28 | 80.47 ± 1.61b | 66.02 ± 1.70α | 69.90 ± 2.14 | 59.42 ± 1.85δ |
Triglycerides (mg/dL) | 33.29 ± 1.57 | 51.07 ± 0.86c | 28.98 ± 1.58δ | 40.82 ± 6.69 | 37.94 ± 3.26β |
HDL-cholesterol (mg/dL) | 30.28 ± 3.62 | 11.15 ± 0.64b | 24.18 ± 3.27δ | 18.87 ± 0.50 | 17.02 ± 2.69 |
LDL-cholesterol (mg/dL) | 28.21 ± 4.47 | 45.52 ± 3.65b | 36.04 ± 3.31 | 42.87 ± 1.58 | 34.81 ± 2.81 |
Cardiac risk ratio | 2.15 | 7.22a | 2.73β | 3.70δ | 3.49δ |
Atherogenic index | 0.04 | 0.66 | 0.08 | 0.34 | 0.35 |
Data are mean ± SEM (N = 6 per group). ANOVA + the Tukey test: cp < 0.05, bp < 0.01, and ap < 0.001 vs. the normotensive control group; δp < 0.05, βp < 0.01, and αp < 0.001 vs. the hypertensive control group. AD100/AD200 = extract doses 100 or 200 mg/kg. LN = N-NAME.