Table 5.
Effects of A. digitata on blood indicators of liver and kidney functions in hypertensive rats.
| Normotensive control | Hypertensive control | LN + captopril | LN + AD100 | LN + AD200 | |
|---|---|---|---|---|---|
| ASAT (UI/L) | 116.7 ± 6.13 | 179.7 ± 11.52a | 76.5 ± 7.31α | 94.8 ± 9.74α | 106.6 ± 7.22α |
| ALAT (UI/L) | 41.6 ± 1.36 | 55.3 ± 4.37b | 39.9 ± 2.09β | 38.4 ± 1.81β | 38.1 ± 1.64β |
| Total protein (mg/dL) | 1.3 ± 0.08 | 2.4 ± 0.11a | 1.8 ± 0.52β | 1.8 ± 0.05β | 1.8 ± 0.07β |
| Creatinine (mg/dL) | 4.8 ± 1.68 | 15.6 ± 1.29a | 4.9 ± 0.28α | 6.5 ± 0.28α | 3.5 ± 3.12α |
| Sodium (mEq/L) | 115.4 ± 1.89 | 139.4 ± 8.03b | 116.8 ± 1.63α | 100.6 ± 2.97α | 86.6 ± 7.38α |
| Potassium (mEq/L) | 10.9 ± 0.14 | 6.1 ± 0.06b | 8.8 ± 0.05β | 11.6 ± 0.36α | 15.2 ± 0.59α |
| Chloride (mEq/L) | 87.6 ± 1.23 | 93.0 ± 0.91c | 87.9 ± 0.30δ | 80.3 ± 0.21α | 86.0 ± 0.97β |
Data are mean ± SEM (N = 6 per group). ANOVA + the Tukey test: bp < 0.01 and ap < 0.001 vs. the normotensive control group; δp < 0.05, βp < 0.01, and αp < 0.001 vs. the hypertensive control group. AD100/AD200 = extract doses 100 or 200 mg/kg. LN = N-NAME.